Document Details

Document Type : Article In Journal 
Document Title :
Flow Cytometric Analysis of Hyperfractionated and Hypofractionated Radiotherapy for Breast Cancer Patients
استخدام تحليل التدفق الخلوى لفحص جرعات اعلاج الاشعاعى المكثف و العادى لمرضى سرطان الثدى
 
Subject : Medical Physics 
Document Language : English 
Abstract : Breast cancer is the most common cancer among women in the world especially in Arabic countries. Thus our study is considered a continuing effort in treatment of such cancer. Our study concerned a comparison between the effect of hyperfractionation radiotherapy (HFRT) which is a high dose per fraction for a short term course and hypofractionation radiotherapy (HRT) which is a low dose per fraction for a long term course of treatment photon doses on breast cancer cells. The comparison is done with refereeing normal breast tissue by flowcytometric (FCM) analysis of DNA ploidy studies. Our samples were extracted from patients whom were irradiated by linear accelerator of 6 MV (Varian model) at radiology department of National Cancer Institute (NCI), Cairo University, Egypt. FCM analysis showed a low S-phase fraction (SPF) letter than 7 % in HRFT, however, it is showed a higher SPF greater than 10% in HFT. According to this concluded results, our study revealed the importance of HFRT for breast cancer patient which give a positive results in killing larger DNA cell populations. 
ISSN : 000002474-6797 
Journal Name : Mathews Journal of Cancer Science 
Volume : 2 
Issue Number : 1 
Publishing Year : 1438 AH
2017 AD 
Article Type : Article 
Added Date : Thursday, February 2, 2017 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
حسام السيد دنيا محمود معوض --, Hossam Elsayed Donya Mahmoud MewadInvestigatorDoctoratehdunia@kau.edu.sa

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